When it comes to handling critical substances, an uncontaminated environment is of high importance
Contamination control
Supply air needs to be filtered in three stages with a HEPA filter at the third stage
Low turbulence airflow above the critical areas (almost laminar)
Overpressure to the neighbouring rooms needs to be maintained at ca. 15Pa - in case of handling hazardous materials, low pressure needs to be maintained and exhaust air must be filtered highly efficient
All surfaces inside of the room should be smooth and easy to clean – rounded corners, reduced numbers of joints